ResearchResearch paperRobotics & Embodied AI · Image, Video & 3D Generation · Computer Vision1 source · Oct 6, 2026

Deformable CT-US Registration via Anatomy-Aware Implicit Neural Representations

In this work, we introduce a deformable CT-ultrasound registration framework that incorporates anatomical priors derived from CT to improve registration under deformation.

Key points

  • Slice-to-volume registration between ultrasound (US) and preoperative computed tomography (CT) imaging would enhance many minimally invasive interventions, for example by locating soft tissue structures intra-operatively that are discernible in CT.
  • While optical tracking enables initial rigid registration, contact from the probe induces soft tissue deformations that inhibit accurate alignment.
  • Rigid registration is first established using a robot-assisted optical tracking system, after which a deformable transformation is estimated using a sinusoidal implicit neural representation (SIREN) optimized per frame.
  • Tissue stiffness is approximated from CT-based HU values and used as spatially varying regularization, suppressing deformation in rigid structures such as bone while allowing more flexibility in soft tissue.

Sources (1)

  • [1]Deformable CT-US Registration via Anatomy-Aware Implicit Neural Representations
    arXiv (AI, ML, NLP, CV, robotics, multi-agent) · Oct 6, 02:22 PM
    In this work, we introduce a deformable CT-ultrasound registration framework that incorporates anatomical priors derived from CT to improve registration under deformation.
    Slice-to-volume registration between ultrasound (US) and preoperative computed tomography (CT) imaging would enhance many minimally invasive interventions, for example by locating soft tissue structures intra-operatively that are discernible in CT.

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