ResearchResearch paperComputer Vision1 source · Oct 7, 2026

CIRSeg: Coarse-to-Fine Intensity-Robust Liver Segmentation with Source-Free Continual Test-Time Adaptation

To address these challenges, we propose CIRSeg, a coarse-to-fine, intensity-robust liver segmentation framework based on nnU-Netv2.

Key points

  • Reliable liver segmentation in contrast-enhanced MRI is essential for quantitative hepatic assessment, treatment planning, and longitudinal disease monitoring.
  • Moreover, simultaneously achieving robust global localization and precise boundary delineation remains challenging, while predictions may contain isolated false-positive regions outside the main liver component.
  • CIRSeg combines 3D CutMix with stochastic intensity transfer using either Nyul augmentation or histogram matching to improve robustness to heterogeneous MRI intensities.
  • Its cascaded architecture decouples low-resolution anatomical localization from full-resolution boundary refinement.

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