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Product / feature launchApplications · Multimodal Models · Agents & Tool Use1 source · Sep 29, 2026

Introducing Quine: An AI research system designed for the complexity of biology

Quine (opens in new tab) is a research effort to create a multimodal world model of biology and an interactive harness connecting models, scientific tools, literature, and researchers.

Key points

  • In collaboration with researchers at the Broad Institute of Harvard and MIT, we have used this system to prioritize compounds predicted to drive therapeutic tumor-state shifts and validated several top-ranked candidates across multiple wet-lab assays.
  • Quine is experimental research technology intended only for research, not clinical or medical use, and its outputs may be incomplete or inaccurate and require review by qualified researchers and appropriate scientific and experimental validation.
  • Genes influence proteins; proteins interact within cells; cells organize into tissues; and experiments continually reshape what scientists know and what they choose to ask next.
  • Today, Microsoft Research is introducing Quine (opens in new tab), a research effort designed to work across those boundaries, reflecting our long-term vision for a discovery system that evolves through scientific use.

Sources (1)

  • [1]Introducing Quine: An AI research system designed for the complexity of biology
    Microsoft Research Blog · Sep 29, 02:00 PM
    - Quine (opens in new tab) is a research effort to create a multimodal world model of biology and an interactive harness connecting models, scientific tools, literature, and researchers.
    - In collaboration with researchers at the Broad Institute of Harvard and MIT, we have used this system to prioritize compounds predicted to drive therapeutic tumor-state shifts and validated several top-ranked candidates across multiple wet-lab assays.

Extractive summary: sentences quoted from the sources.