Analysis
Opinion, explainers and guides from people worth reading.
VideoSonarQube + OpenAI: Agentic Development — Killian Carlsen-Phelan, Sonar
Killian Carlsen-Phelan runs it through SonarQube, brings the findings into Codex and asks the agent to fix the vulnerable query.
AI agents overstate their results and remain far from autonomous research, study finds
Epoch AI and Anthropic independently found the same thing: current AI models like GPT-5.6 Sol and Claude Fable 5 can run experiments but lack scientific self-criticism and genuine creative thinking.
Quoting The New York Times
— The New York Times, Anthropic Agents Tried to Fill Out Visa Forms on State Dept.
Why AlphaFold Didn't Solve Protein Folding — Pushmeet Kohli, Google DeepMind & Sal Candido, Biohub
From the Bitter Lesson of AI scaling to the unsolved mysteries of protein folding, Google DeepMind’s Pushmeet Kohli and Biohub’s Sal Candido are rethinking what it takes to build AI that truly understands biology.
Is a second MSc worth it? [D]
I’m an AI research engineer based in Africa with about 3 YoEs in RL, LLMs, post-training, and systems efficiency (CUDA/vLLM).
OpenMed 3.0 is out: Apache-2.0 clinical AI that runs fully local and never falls back to the cloud. 422 open issues if you want in on 3.1
Quick recap: it's an open-source (Apache-2.0) medical AI toolkit with one rule we never break: patient data stays on your machine.
Amazon and others are done keeping data center deals secret. Is it enough to build trust?
Amazon says it will stop using NDAs when negotiating data center deals with local governments, following a similar move from Microsoft earlier this year.
Pollo AI turns creative ideas into campaigns with OpenAI
With GPT-5.6, GPT-6 Astra, and GPT‐Image‐2.5, Pollo AI helps creators turn bold ideas into detailed images and cinematic video ads.
Instinct was the buzziest AI agent around — can it survive Muse?
Instinct’s agent is always just a text away.
VideoWhat Most People Get Wrong About Evolution | Akarsh Kumar
A lot of people in AI treat evolution as a dumb fallback, basically random search for when you can't take a gradient.
She Designed Meta’s New AI Logo. Then Came the Hate
Jessica Hische knew working for Meta might upset some people.
The Epoch Brief - October 8, 2026
Welcome back to the Epoch Brief.
Text is so 2023
Hark (from Brett Adcock - Figure robots) launched which suggests tasks as one-tap action buttons.
The State of AI Report 2026
After months of research and revisions right up to the last minute, I’m thrilled to bring you the 9th annual State of AI Report.
Flahy uses knowledge graphs to support AI-powered healthcare
The post Flahy uses knowledge graphs to support AI-powered healthcare appeared first on SiliconANGLE.
Show HN: I Put an AI Agent on a Nokia 110
Recently got the idea to put ai agent in it.
Rethinking access control for RAG with Amazon Quick and Amazon Bedrock
Enterprise organizations are adopting Retrieval Augmented Generation (RAG) to unlock insights from company knowledge sources like Microsoft SharePoint, Google Drive, and Atlassian Confluence.
Lune
The search engine built for scientific AI agents
The U.S. Nuclear Plant Fleet Is Leaning Into AI
If there is any place that would be off-limits to AI, the control room of a nuclear power plant certainly sounds like one.
Does better work always mean better workers?
But AI is already changing how on-the-job learning works.
AI coding agents generate more code, but not more software
A recent study of actual coding practices across hundreds of firms finds that human code review forms a significant "bottleneck" for the overall efficiency of AI coding tools, resulting in "little evidence that firms increase software output or reduce employment" by using them.
What AI gets wrong and what failure teaches us
Jennifer Neville is a partner research manager at Microsoft who’s built a career around understanding and advancing AI for real-world use, and much like the human-AI interactions she’s been studying, her early-career path was multiturn: math, then physics; cognitive science, then work; and finally computer science—despite her best efforts to avoid the field.
Roundtables: A Conversation With the Creator of AI-Designed Viruses
In 2025, Stanford University PhD student Samuel King came up with a preliminary answer when he used a generative AI model to propose genetic blueprints for microscopic viruses.
VideoThe Billion Dollar AI Advantage Is Disappearing
🙏 We would like to thank our generous Patreon supporters who make Two Minute Papers possible:
Negotiating Ontological Boundaries in User-Authored Personal Sensing Systems
Negotiating Ontological Boundaries in User-Authored Personal Sensing Systems
VideoBuilding Self-Learning Loops for Your Agent — Fuad Ali, Arize AI
A shopping assistant confidently returns products outside a user's budget because its price filter is broken.
VideoHow to Build Quality Gates into Agentic Coding Workflows — Nnenna Ndukwe, Qodo AI
Nnenna Ndukwe uses SignalPay, a deliberately narrow FastAPI payments application, to turn that sequence into quality gates for an AI coding agent.
Cheaper AI tokens are driving more demand, and that's Jensen Huang's best-case scenario
Data from a16z shows a Jevons paradox in the AI market: token prices keep falling, but H100 GPU rental prices hold steady or climb.
VideoLet Your Agent Cook: Using Skills to Evaluate and Improve Your App — Ankur Duggal, Arize AI
A financial agent invents answers, repeats tool calls and produces summaries that its own evaluations flag as wrong.
Dwarf Fortress uses version control now
I remember hearing a while ago that Dwarf Fortress didn't use version control.
Can the AI industry persuade data center opponents by getting rid of NDAs?
On Equity, we debate the impact of data center moratoriums and whether the AI industry has a communication problem.
ArXiv caps submissions at two per month as AI paper flood overwhelms the preprint server
Starting October 2026, arXiv will cap submissions at two per person per month.
What ai is best to operate a system from screen video [p]
I have working programmatic control over a system, I can send inputs reliably and capture the screen as visual feedback.
Maildun for Mac
Design on-brand emails by hand, with AI, or over MCP
AI Is Getting Really Good at Messing With Cybercriminals
Anti-cybercrime initiatives are increasingly using AI to scam the scammers by tricking them into talking to lifelike bots that they think are real victims.
Few people pay for AI, but those who do spend big
Andreessen Horowitz tracks actual US consumer spending for the first time in its latest Top 100 AI list.
AI reshapes professional services around trust and business outcomes
Professional services firms are rethinking how they deliver client value as artificial intelligence takes on more routine work, shifting attention toward human judgment, trusted outcomes and new operating models.
Building AI builders: Playbook for closing the AI knowledge-capability gap
The biggest barrier to AI adoption isn’t awareness.
Ben Affleck is an AI nerd, and the internet is impressed
Ben Affleck is going viral for his deep knowledge of AI, from neural networks and transformers to open weights.
How Qlik built grounded, enterprise-scale AI with Amazon Bedrock
Building grounded AI on Amazon Bedrock, Qlik Answers tackles a common enterprise problem: employees aren’t short on data.
Book Publishers Are Quietly Using More AI. Staff Are Revolting
Workers at three major publishing houses tell WIRED that LLMs are being used for publicity, cover art, back cover copy, and emails, as some execs push junior staff to champion the tech.
Helping teens learn, plan, and shape the future of AI
College Planner is coming to ChatGPT for Teens to help students manage college applications, alongside new flashcards, quizzes, and a teen AI council.
“Software is over”: Bold AI developer takes aim at Adobe with open source clones
In announcing those new apps on Reddit earlier this week, software developer Brandon Thomas said he used Anthropic's Claude Opus 5.5 to create "clean-room replacements" for Adobe's closed source software in Rust (with WebAssembly versions available for use in a browser).
We can’t help treating AI like it’s human. But should we?
"When we are drawn into even the most primitive exchanges with a relational artifact, we believe it cares for us," Dr. Sherry Turkle writes.
a16z’s Olivia Moore on the state of consumer AI
Moore sees a huge opportunity in consumer AI, particularly if the industry can tap into revenue streams beyond just subscriptions and API charges.
Trump’s attempt to rename AI is looking awfully artificial
President Donald Trump has a knack for turning words against his enemies.
Responsible AI governance: How AWS positions customers to align with ISO/IEC 42005:2025
With generative AI adoption moving faster than the personal computer or the internet and global AI-related investment in 2025 representing $581.69 billion, organizations must position their workforce to use AI to power their operations while employing it responsibly.
These Researchers Made AI Drive a Toyota Corolla to Get In-N-Out
Three engineers put GPT, Claude, and Grok in charge of a real car.